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• \documentstyle 12pt,fullpage,psfig,simplemargins,doublespace {report} \title{Sleep and Sleep Deprivation} \author{Roger Dingledine \\ 9. 00: Introduction to Psychology } \date{\today} \setleftmargin{1in} \setrightmargin{1in} \settopmargin{1in} \setbottommargin{1in} \renewcommand{\thesection}{\arabic{section}} \setlength{\parindent}{5em} \begin{document} \maketitle \newpage Since the beginning of recorded history, humans have been curious about the functions of sleep. Though the specific needs that sleep fulfills are still for the most part unknown, it is clear that the act of sleep is necessary to maintain our awareness and ability to interact with our environment. The effects of sleep deprivation, or an extended partial or total loss of sleep, are interesting from a scientific viewpoint for several reasons. First, studying sleep deprivation gives us a better understanding of the purpose of sleep itself. By preventing the body from receiving its normal amount of sleep, we can determine which processes are affected, and how much a given amount of sleep loss affects them. Second, the practical consequences of loss of sleep can be determined -- the extent to which it interferes with physical or mental activity, and which activities are affected most and least. Third, examination of people who have endured extended loss of sleep allows us to understand more fully its effects on mental and physical health. Today, sleep deprivation plays a role in the lives of many important people in our society. Sleep deprivation study can be approached in several different ways in order to gain insight into the functions of sleep itself. By selective deprivation of only certain parts of the sleep cycle, we can determine the functions of those stages of sleep, and their importance to the body and mind.

• » Sleep Deprivation.
• Please help before my husband and I die of sleep deprivation! Our son who is 21months old didn't sleep through the night until he was one. ...
• Even if you get a few missed nights sleep until he settles, hopefully he will eventually get the idea if you refuse to join him or play with him. Also, how much sleep is he getting in the day time? It may be worth cutting down his nap times to an hour (don't let him sleep at all in the evenings until bedtime) and maybe even moving his bedtime slightly later in order to get him to sleep in longer in the mornings. ...
• Humans are the only "animals" that put our babies away from us to sleep. I do admit it's not always practical, but if it's only for the last few hours in a morning or early hours then why not? Who says they have to sleep apart from us? That way you all get some sleep! They are babies for such a short time; enjoy the cuddles! .
• My daughter Robyn didn't sleep through until she was two and in her own bed! I can't say that this is why she all of a sudden slept through, but everything we tried didn't work and as soon as she was in her own bed she slept! Maybe it might work; you never know! .

• Most Americans are chronically sleep-deprived. However, few people are aware of the extent to which sleep deprivation impairs cognitive functioning. ...
• Consequences of Sleep Deprivation.
• Although the function(s) of sleep remain unknown, evidence clearly shows that sleep deprivation has severe physiologic consequences. In rats, total sleep deprivation (both NREM and REM) is fatal within about three weeks (similar to the survival time associated with total food deprivation), and isolated REM sleep deprivation is fatal in about six weeks. ...
• Humans cannot be ethically deprived of sleep long enough to result in any known medical consequence, as sleep eventually supervenes regardless of the technique of sleep deprivation. Therefore, to the extent that sleep deprivation is possible in humans, the only known consequence is severe sleepiness, which represents a wake-state instability resulting in irritability, negative mood, and impaired cognition and performance—particularly in tasks resulting in sustained attention. 7 Although the consequences of sleep deprivation may be subtle, they interfere with some of the most important cognitive processes, including those pertaining to creativity, abstract thinking, and the control of attention and emotion. ...
• Many in our society grow up being taught that sleep deprivation is to be worn as a "badge of honor," that sleepiness is a minor annoyance that can be overcome by motivation, commitment, dedication, or sheer will. ... Sleep is a biological imperative. The consequences of sleep deprivation are cumulative, with escalating performance and mood ramifications. 12 One does not "get used to" sleepiness: Accumulated sleep debt is dissipated only by catch-up sleep. To make matters worse, the relentless move toward a 24-hour society encourages chronic sleep deprivation.
• The homeostatic factor is related to the duration of prior wakefulness: the longer the duration of wakefulness, the greater the pressure to sleep. ... Other factors that determine degree of sleepiness include age, underlying undiagnosed sleep disorders, and the effects of alcohol and some medications.
• Many believe that sleepiness-related decrements in performance are due to frank "micro-sleep" episodes. Impairment of vigilance and reaction time precedes the appearance of true physiologic sleep; a sleepy individual who appears to be "awake" may actually be significantly impaired. 16 Sleep deprivation results in errors even in the absence of electrophysiologically defined sleepiness; after one night’s sleep deprivation, the brain is functioning at a lower level at all times. 17 Amplitude reduction in visual event–related potentials as a result of sleep deprivation exemplifies fundamental changes in neurophysiologic mechanisms, indicating variability and reduction of alertness mechanisms and changes in thalamocortical gating affecting attention, discrimination, and decision making. 18 The lack of awareness of the extent to which sleep deprivation impairs cognitive functioning has been well-documented. 19 Consistent with the concept that the brain is the only organ benefiting from or requiring sleep is the fact that sleep deprivation results in CNS impairments, but not physical ailments. 20 (As an aside, the previously held notion that rapid-eye movement REM sleep deprivation in humans results in psychiatric or psychological problems is not true. ...

• Sleep Deprivation Chamber.
• The Department of Theatre will perform the play Sleep Deprivation Chamber, which Kennedy co-authored with her son, Adam P. ...
• ” In Sleep Deprivation Chamber, for example, Teddy is a young African American who is stopped late at night by the police less than a block from his Arlington, Va. ...
• Sleep Deprivation Chamber.

• Health > Centers > Depression Center > Treating Depression > Types of Treatments > Other Treatments > Sleep Deprivation .
• Sleep Deprivation.
• Sleep Disorders Health Center .
• While Mom--and studies--agree that you won't perform your best without a good night's sleep, skipping slumber may be a good idea for people with severe depression. ...
• For decades, spontaneous reports from patients suggested that sleep deprivation can alleviate depression. ... Next, Wu had all 36 subjects skip a night of sleep, after which the same one-third reported feeling better. ... Still, some doctors already use sleep deprivation to treat serious depression. ...
• He reports in the journal Nature that the brain's parietal lobes, which assist only with math in a rested head, became activated while sleep-deprived subjects were trying to recall a word list, apparently to compensate for fatigue. ...

• Effects of Sleep Deprivation on Neural Circulatory Control .
• Abstract—Effects of sleep deprivation on neural cardiovascular control may have important clinical implications. We tested the hypothesis that sleep deprivation increases heart rate, blood pressure, and sympathetic activity and potentiates their responses to stressful stimuli. ... Measurements were obtained twice, once after normal sleep and once after a night of sleep deprivation. ... In comparison with normal sleep, sleep deprivation resulted in an increase in blood pressure (normal sleep versus sleep deprivation=82±8 versus 86±7 mm Hg, mean±SEM, P=0. 012) and a decrease in muscle sympathetic nerve activity (normal sleep versus sleep deprivation=28±6 versus 22±6 bursts/min, P=0. ... Heart rate, forearm vascular resistance, and plasma catecholamines were not significantly changed by sleep deprivation, nor did sleep deprivation affect autonomic and hemodynamic responses to stressful stimuli. Sleep deprivation results in increased resting blood pressure, decreased muscle sympathetic nerve activity, and no change in heart rate. Thus, the pressor response to sleep deprivation is not mediated by muscle sympathetic vasoconstriction or tachycardia. ...
• Key Words: sleep deprivation • sympathetic nervous system • vascular resistance • catecholamines.
• Chronic sleep deprivation affects at least one third of normal American adults. 1 In animal studies, several days of complete sleep deprivation results in an increase in mortality. 2 It has been suggested that fragmented sleep or sleep deprivation may increase the incidence of cardiovascular events. ...
• 8 9 10 Lusardi et al11 noted that in hypertensive patients, sleep deprivation induced increases in BP, HR, and urine norepinephrine on the morning after a night of inadequate sleep. Several studies have proposed the attractive hypothesis that activation of the sympathetic nervous system by sleep deprivation may be implicated in triggering cardiovascular events in the morning hours. 11 12 13 We are unaware of any direct studies of sympathetic responses to sleep deprivation. We therefore tested the hypothesis that sleep deprivation increases HR, BP, and sympathetic activity and potentiates their responses to stressful stimuli. ...

• World Federation of Sleep Research Societies .
• Prostaglandin D2 and nitric oxide: key 0134 yawning elicited by D2 dopaminergic agonists 0171 icipation of D1 and D2 dopaminergic receptors 0451 r the prostaglandin D2-sensitive, sleep-promo 0149 lation by light and dark in congenic albino a 0254 ude to the onset of darkness. ... Study of circ 0536 of age and time of day on sleep-spindle acti 0503 leep onset latency. ... Insuffi 0288 but suppression of daytime NREM sleep after 0029 nin formulations on daytime sleep and mood. E 0546 shifts on mood and daytime sleep. Direct ver 0531 EEG activity during daytime sleep. ... Imp 0535 nocturnal sleep and daytime somnolence. ... Night's sleep and daytime well-being in sle 0302 ght exposure in the daytime. ... Ya 0081 c mice show a rapid decline in Fos-LI and b-g 0062 e wakefulness level decrease (attention and f 0248 sleep deprivation. Decrease of microtubule d 0439 n the intact cat is decreased during active s 0063 opposite effects on deep slow wave sleep and 0119 s increase as sleep deepens in rats. Sleep sp 0014 ive neurobehavioral deficits during waking. A 0427 Neuropsychological deficits in obstructive s 0348 fter a 6-hour phase delay of the light-dark c 0534 atment of a case of delayed sleep phase syndr 0513 lopentyltheofylline delays but does not block 0158 plication.

• home > productions > 2002-2003 season > Sleep Deprivation Chamber.
• Scene from Sleep Deprivation Chamber, OSU Spring 2003.
• Scene from Sleep Deprivation Chamber, OSU Spring 2003 Scene from Sleep Deprivation Chamber, OSU Spring 2003 Scene from Sleep Deprivation Chamber, OSU Spring 2003 Scene from Sleep Deprivation Chamber, OSU Spring 2003 .
• Sleep Deprivation Chamber.

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• Suffering From Sleep Debt? The Dangers of Chronic Sleep Deprivation .
• — Are you getting enough sleep? How much is enough?.
• David Dinges, Chief of the Division of Sleep and Chronobiology, in the Psychiatry Department of the University of Pennsylvania, estimates that only 10 percent of Americans can consistently sleep fewer than eight hours per night without harming their health.
• "If you're a nine or a nine and a half-hour need, and you're sleeping eight, you're developing a sleep debt," says Dinges. ...
• New studies show that sleep deprivation can accelerate the aging process, lead to obesity and increase the risk of some diseases. ...
• David Dinges, chief of the Division of Sleep and Chronobiology in the department of Psychiatry at the University of Pennsylvania School of Medicine. ...
• Dinges, how can you tell if you're getting enough sleep? .
• If you are sleepy frequently, or intensely, for even brief periods during the daytime, then it's likely you're not obtaining adequate amounts of quality sleep, even if you're spending adequate amounts of time in bed for sleep. ...
• Some people with sleep disorders spend time in bed, but do not sleep restfully. Others who do not have sleep disorders simply do not spend enough time in bed sleeping. Either way, you can develop a significant sleep debt and become impaired by sleepiness during the daytime, or at night when you're attempting to work or play. ...
• Is there such a thing as too much sleep? How much is too much? .
• Although many people believe you can obtain too much sleep, this really isn't possible physiologically. The brain, which is the organ that needs sleep and ensures that the body obtains sleep, will wake up when it's had enough sleep. ...
• Some sleep disorders will awaken the sleeper spontaneously, not because the brain has had enough sleep, but because there is a problem in the body or the brain that makes it unable to sustain sleep. ...
• The bottom line is: You really cannot oversleep beyond your basic sleep need. ...

• Sleep Deprivation .
• , 6 hours after you went to sleep (Anonymous 2). More than half of all teenagers are sleep-deprived. The National Sleep Foundation says that 63% of adults get less than their recommended 8 hours of sleep (Kowalski 16). If you get less than eight hours of sleep per night and you are a teenager, more than likely you are sleep deprived. The National Sleep Foundation says that most teens need at least 8 ½ hours of sleep every night, but only about 15% get that amount (Anonymous 2). In a collection of data recently studied a chart was provided on the hours of sleep children should be getting. ...
• Children Needing Varying Amounts of Sleep as they Grow .
• Sleep (Hours).
• Studies show that when in teenage years that’s when they need at least eight to nine hours of sleep each night. ... 2 hours of sleep they need each night for optimal functioning (Kowalski 16). Without this need being met after awhile sleep deprivation develops. When this occurs the body can not function properly and the body can do less each day that it does not get enough sleep, especially at school or a job. When students do not get enough sleep it leads to a lack of motivation and attention in classes, leading to a drop in grades in classes. ...
• Sleep Deprivation is a lack of sleep. ... More than seventy percent of all teens suffer from Sleep Deprivation and more than half of all adults do. 25% of all teens get less than 7 hours of sleep each night (Anonymous 2). Since most teenagers go through their day tired and half asleep, some of their bad grades could be the result of this sleep deficit. Teenagers should be getting at least eight to nine hours of sleep each night. Adults don’t need quite as much but should be getting somewhere in between seven and eight hours of sleep per night. Some people make the false assumption that they can get through their day with a few less hours of sleep. By losing sleep a person is further lengthening the day in which they perform their activities. When those activities start cutting into sleep, the process begins where that person will constantly feel bogged down and unable to perform tasks within a reasonable amount of time. ...

• Topic: sleep deprivation.
• " Diagnosis and Treatment of Sleep Disorders. ...
• "Sleep Loss leaves us Vulnerable. ...
• "A teen thing: Losing Sleep. ...
• "Are you Getting Enough Sleep?" Maclean's 113. ...
• "The Power of Sleep. ...
• "Sleep The Final Frontier. ...
• "A Rude Awakening on Sleep Deprivation. ...

• educate employees about strategies that enhance sleep and reduce fatigue .
• Our goal is to help you Sleep Better, Feel Better and Work Better.

• AMERICAN SLEEP APNEA ASSOCIATION .
• What is Sleep Apnea?.
•   Being Evaluated for Sleep Apnea.
•   Sleep and the Internet.
•   Sleep Apnea and Same-Day Surgery.
• American Sleep Apnea Association.
• The ASAA is a 501(c)(3) organization dedicated to reducing injury, disability, and death from sleep apnea and to enhancing the well-being of those affected by this common disorder. ...

• relevance of hallucinations, it seems to be clear that their occurrence strongly correlates with two extremes of sensory activation: either sensory flooding (sensory overload) or sensory deprivation. Both, of course, may be caused by external (as rave party or solitude) or internal factors (as drugs, brain injury, illness, or sleep deprivation). ...
• I think many of the hallucinatory sensory deprivation effects were found to be demand characteristics. ...

• Insomnia, sleep disorders and sleep deprivation.
• Ayurveda Home Remedies Home Remedies Insomnia, sleep disorders and sleep deprivation.
• Home remedies for insomnia, sleep disorders and sleep deprivation :.
• Keep the eyes closed and sleep. ...
• What is Ayurveda ? - sleep - headaches - constipation - cold - stomach - healing stones & birthstones - more.
• ""People who sleep seven to nine hours aren't sleeping. ...

• Sleep Tips 6 .
• Body Heating and Sleep 8 .
• About half of Americans report sleep difficulty at least occasionally, according to National Sleep Foundation surveys. ...
• Fortunately, there are many things you can do to improve your sleep. ... As you begin to see the connection between, for example, what and/or when you eat and nights of poor sleep, you can develop your own good sleep plan. ...
• Keep in mind that good sleep doesn't always just happen. ... If you've been sleeping poorly for some time, you may have fallen into some bad sleep habits that reinforce your problem. Read on to learn more about sleep. ...
• But that same drink can prove an enemy of restful sleep. ...
• However, while alcohol may speed the beginning of sleep, it actually increases the number of times you awaken in the later half of the night. If your sleep isn't restful, alcohol (beer, wine, hard liquor) may be the cause. Skip the nightcap and see if your sleep improves. ...
• Are You What You Eat? Caffeine and alcohol aren't the only substances that affect your sleep. ... What does heartburn have to do with sleep? Lying down makes heartburn worse, and heartburn itself makes falling asleep more difficult. ...
• Try to restrict your fluids before bedtime to help promote an uninterrupted night's sleep. ...
• Another cause of sleep problems can be eating too much - of any food - that can make sleep difficult. ... At the same time, going to bed hungry can be just as disruptive to sleep as going to bed too full. ...

• Back to: eMedicine Specialties > Neurology > Sleep Related Diseases .
• Normal Sleep, Sleep Physiology, and Sleep Deprivation: General Principles.
• Synonyms and related keywords: non–rapid eye movement, NREM, rapid eye movement, REM, stage I sleep, light sleep, stage II sleep, stage III sleep, stage IV sleep, deep sleep, delta-wave sleep.
• Author Information Normal Sleep In Adults, Infants, And The Elderly Sleep Physiology Circadian Rhythms That Influence Sleep Effects Of Sleep Deprivation Bibliography.
• Michael B Russo, MD, is a member of the following medical societies: Aerospace Medical Association, American Academy of Neurology, American Academy of Sleep Medicine, and American Epilepsy Society.
• NORMAL SLEEP IN ADULTS, INFANTS, AND THE ELDERLY .
• Author Information Normal Sleep In Adults, Infants, And The Elderly Sleep Physiology Circadian Rhythms That Influence Sleep Effects Of Sleep Deprivation Bibliography.
• Normal sleep is divided into non–rapid eye movement (NREM) and rapid eye movement (REM) sleep. The stages of sleep are stage I (light sleep), stage II, stages III and IV (deep or delta-wave sleep), and REM sleep; NREM sleep comprises stages I-IV. Sleep is an active process that cycles at an ultradian rhythm of about 90 minutes. ...
• Waking usually transitions into NREM sleep. REM follows NREM sleep and occurs 4-5 times during a normal 8- to 9-hour sleep period. ...
• For the purpose of analysis, overnight sleep has been divided into 3 equal time periods: sleep in the first third of the night, which comprises the highest percentage of NREM; sleep in the middle third of the night; and sleep in the last third of the night, the majority of which is REM. Awakening after a full night’s sleep is usually from REM sleep. ...
• Sleep in adults .
• In adults, sleep of 8-8. ... In some cultures, total sleep often is divided into an overnight sleep period of 6-7 hours and a midafternoon nap of 1-2 hours. ...

• Sleep Deprivation Impairs Long-Term Potentiation in Rat Hippocampal Slices .
• Sleep Deprivation Impairs Long-Term Potentiation in Rat Hippocampal Slices. ... To determine if 12-h sleep deprivation disrupts neural plasticity, we compared long-term potentiation (LTP) in five sleep-deprived and five control rats. Thirty minutes after tetanus population spike amplitude increased 101 ± 15% in 16 slices from sleep deprived rats and 139 ± 14% in 14 slices from control rats. ... 05) reduction of LTP, the first demonstration that the sleep deprivation protocol impairs plasticity in adult rats, may be due to several factors. Reduced LTP may indicate that sleep provides a period of recuperation for cellular processes underlying neural plasticity. Alternatively, the stress of sleep deprivation, as indicated by elevated blood corticosterone levels, or other non-sleep-specific factors of deprivation may contribute to the LTP reduction. ...
• Homeostatic models of slow wave sleep propose that sleep serves a recuperative function for the brain (Borbely 1982; Feinberg 1974). Moruzzi (1966) suggested that the restorative processes of sleep provide recovery specifically from the plastic activities of waking. One prediction based on Morruzzi's proposal is that sleep deprivation should impair plasticity. ... As a test of whether sleep deprivation disrupts plasticity, we determined if LTP is impaired in hippocampal slices from sleep-deprived rats. ...
• Sleep deprivation .
• Rats were deprived of sleep via forced locomotion in a slowly (1. ... All 10 rats were trained to the sleep deprivation device in successive sessions of 30-, 45-, and 60-min duration. Five of the 10 rats were individually placed in the deprivation device for the entire 12-h light period, the typical rest period for rats. Rats were removed from the deprivation device at the end of the light period (prior to lights off) and decapitated within 5 min of removal. ...

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• BEHAVIOURAL AND EEG EFFECTS OF PARADOXICAL SLEEP DEPRIVATION IN THE CAT.
• Since the work of Pieron (1913) 18, the effect of sleep deprivation has been largely studied both in man and animaIs. But the problem of sleep has become complicated recently by the demonstration that sleep could not be considered as a unique phenomenon (opposed to wakefulness), but on the contrary was composed of two different neural states, being most probably the expression of different mechanisms: sleep with synchronized EEG activity = slow sleep (S. ... ) and sleep with desynchronized EEG activity (activated sleep: Dement, 1958 2; paradoxical sleep (P. ...
• deprivation in the cat. ... , the effects of temporary instrumental deprivation of P. ...
• PARADOXICAL SLEEP .
• Paradoxical sleep, in normal cats, always follows a period of slow wave sleep. ... 1963 7) and clonic jerks are the most salient features of this state of sleep which represents 20 to 25% of total sleep (and therefore 15% of the day). ...
• is considered to be the deepest state of sleep since the threshold of arousal by stimulation of the midbrain reticular formation is much enhanced in comparison with S. ... Two main problems are stil1 not solved concerning this state of sleep: the first one concerns the specificity of P. ... would appear as a deep sleep opposed to S. ... considered as a light sleep (Hernàndez-Peon, 1965 6). ...
• INSTRUMENTAL DEPRIVATION OF PARADOXICAL SLEEP .
• A technique of instrumental and selective deprivation of P. ... (Jouvet, Vimont, Delorme and Jouvet, 1964 9) was employed in order to dissociate the two states composing behavioural sleep in normal chronic cats with implanted electrodes. ... Six cats were subjected to successive periods of deprivation of 1, 2, 3, 4, 5, 6, 9, 10, 15, 22 and 26 days. At the end of depfivation, the cats could recover normal sleep in sound-proof cages and were registered continuously until the control level of sleep-waking rhythm reappears. ...

• sleep deprivation .
• Library Home > Book Shelf Home > The Doctors Book of Home Remedies for Women > sleep deprivation .
• Sleep Deprivation Get Your Rest and Feel Good Again .
• Constant daytime sleepiness is the hallmark of chronic sleep deprivation. But some of us are so accustomed to plodding by on too little sleep that we don't even recognize it. ...
• "People may not realize what's going on until they go on vacation and allow themselves the sleep they need," says Margaret L. ... , director of the New York Hospital-Cornell Medical Center Sleep-Wake Disorders Center in White Plains, New York. ... It turns out that they usually sleep only six hours. ...
• MAKING UP A SLEEP DEFICIT .
• Sleep is like money: The longer you go without adequate supplies, the worse your situation gets. ...
• "As the days go on, a sleep deficit accumulates like interest on an unpaid credit card balance," says Mary A. ... , professor of psychiatry and human behavior at Brown University School of Medicine and head of the sleep research lab at E. ... "Say you don't get enough sleep on Sunday night. ...
• But running up a sleep debt can take a heavy toll. ...
• If you're running up a sleep deficit, you may need medical help to resolve the problem, depending on the cause. ...
• , director of the New York Hospital-Cornell Medical Center Sleep-Wake Disorders Center in White Plains, New York. ...

• Sleep Deprivation .
• But then I thought: maybe I'm just that rare type of person who needs no sleep. ... Like sleep is for mortals. I can work forever and never need sleep. ...

• The Sleep, Chronobiology and Neuroendocrinology Group.

• SLEEP PROBLEMS IN BABIES & CHILDREN .
• AFFIRMATIONS TO HELP YOU CALM DOWN AND GO TO SLEEP .
• COPING WITH FEELING WRETCHED FROM SLEEP DEPRIVATION .
• For the Sleep-Challenged Soul.
• COPING WITH FEELING WRETCHED FROM SLEEP DEPRIVATION.
• You've got to get up and function on much less sleep than you would have liked - much less than you need. ...
• Realize you probably won't die from lack of sleep - unless, of course you're required to operate dangerous machinery - in which case you actually could die - or cause someone else to die. A car, by the way, is a dangerous machine - mighty dangerous - especially when the driver is sleep deprived. In fact, recent statistics suggest that sleep-deprived drivers are responsible for as many deaths as intoxicated drivers. ... If you're now sleep deprived - we urge you not to operate dangerous machinery - absolutely do not. ...
• When you're sleep deprived, your defenses will most likely be down. ...
• You probably are somewhat more susceptible to illness when you haven't had adequate sleep. ...
•   Making certain statements to yourself can be helpful, such as, "I am healthy and I am going to stay healthy - even if I didn't get all the sleep I wanted. " Or, "I will be productive today - in spite of my sleep deprivation. ...
•   A giant dose of coffee cannot make up for your lack of sleep - and it won't make you feel a lot better during the day.
• You might find that a spurt of vigorous exercise helps get you going when you're sleep-deprived - even though you might not be inclined to do it under the circumstances. ...

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